7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline
7-Fluoro-4-quinazolone
CAS: 16499-57-3
Molecular Formula: C8H5FN2O
7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline - Names and Identifiers
| Name | 7-Fluoro-4-quinazolone |
| Synonyms | EOS-61781 7-Fluoro-4-quinazolone 7-FLUOROQUINAZOLIN-4-OL 7-Fluoroquinazolin-4-one 7-Fluoroquinazolin-4(3H)one 7-fluoroquinazolin-4(1H)-one 7-Fluoro-1h-quinazolin-4-one 7-fluoroquinazolin-4(3H)-one 7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline |
| CAS | 16499-57-3 |
| InChI | InChI=1/C8H5FN2O/c9-5-1-2-6-7(3-5)10-4-11-8(6)12/h1-4H,(H,10,11,12) |
| InChIKey | KCORZHJVTZIZFD-UHFFFAOYSA-N |
7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline - Physico-chemical Properties
| Molecular Formula | C8H5FN2O |
| Molar Mass | 164.14 |
| Density | 1.44±0.1 g/cm3(Predicted) |
| Melting Point | 246.0 to 250.0 °C |
| Boling Point | 293.3±42.0 °C(Predicted) |
| Flash Point | 131.2°C |
| Vapor Presure | 0.00174mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Gray to Red |
| pKa | 0.51±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.642 |
7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline - Introduction
7-Fluoro-4-quinazolone, chemical formula C8H4FN3O, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 7-Fluoro-4-quinazolone is a white crystal or crystalline powder.
-Melting point: Its melting point is about 160-164°C.
-Solubility: It is soluble in organic solvents such as chloroform, dimethyl ether and alcohol solvents, and insoluble in water.
Use:
-Pharmaceutical field: 7-Fluoro-4-quinazolone can be used to synthesize other organic compounds, and also has certain pharmaceutical properties, which can be used to synthesize pharmaceutical intermediates or drugs.
-Pesticide field: It can also be used as an intermediate of pesticides and has applications in the agricultural field.
Method:
- 7-Fluoro-4-quinazolone can be prepared by a synthetic method. A common synthesis method uses 2-chloro-4-fluorofuran as a starting material and reacts with carbamate under appropriate reaction conditions to generate an intermediate, after further chemical reactions, it is converted to 7-Fluoro-4-quinazolone.
Safety Information:
- 7-Fluoro-4-quinazolone needs to pay attention to safety measures when using and storing.
-It is an organic compound that may be irritating or toxic to the human body, so protective gloves, goggles and protective clothing must be worn when using it.
-Avoid ingesting or inhaling 7-Fluoro-4-quinazolone, especially if it is not properly treated.
-In the event of accidental exposure to the compound, wash immediately with plenty of water and seek medical assistance.
-In storage, it should be kept away from fire sources, heat sources and oxidants, and stored in a dry and well-ventilated place.
-All handling of this compound should follow the relevant safety procedures and guidelines, and please ensure that its nature and operation are fully understood before use.
Nature:
-Appearance: 7-Fluoro-4-quinazolone is a white crystal or crystalline powder.
-Melting point: Its melting point is about 160-164°C.
-Solubility: It is soluble in organic solvents such as chloroform, dimethyl ether and alcohol solvents, and insoluble in water.
Use:
-Pharmaceutical field: 7-Fluoro-4-quinazolone can be used to synthesize other organic compounds, and also has certain pharmaceutical properties, which can be used to synthesize pharmaceutical intermediates or drugs.
-Pesticide field: It can also be used as an intermediate of pesticides and has applications in the agricultural field.
Method:
- 7-Fluoro-4-quinazolone can be prepared by a synthetic method. A common synthesis method uses 2-chloro-4-fluorofuran as a starting material and reacts with carbamate under appropriate reaction conditions to generate an intermediate, after further chemical reactions, it is converted to 7-Fluoro-4-quinazolone.
Safety Information:
- 7-Fluoro-4-quinazolone needs to pay attention to safety measures when using and storing.
-It is an organic compound that may be irritating or toxic to the human body, so protective gloves, goggles and protective clothing must be worn when using it.
-Avoid ingesting or inhaling 7-Fluoro-4-quinazolone, especially if it is not properly treated.
-In the event of accidental exposure to the compound, wash immediately with plenty of water and seek medical assistance.
-In storage, it should be kept away from fire sources, heat sources and oxidants, and stored in a dry and well-ventilated place.
-All handling of this compound should follow the relevant safety procedures and guidelines, and please ensure that its nature and operation are fully understood before use.
Last Update：2024-04-09 20:49:11
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CAS: 16499-57-3
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